Molecular Screening Shared Resource
Delivering High Throughput Screening to the UCLA research community
The services provided include the use of high throughput screening (HTS) technology, a total of roughly 200,000 compounds in various libraries, siRNA sets of the druggable genome for mouse and human and a database of results from screens. Please use the links above to find out more about the MSSR.
The MSSR is currently funded by the JCCC, the Department of Molecular and Medical Pharmacology, the Department of Microbiology, Immunology and Molecular Genetics, and the Dean’s office, David Geffen School of Medicine and the California NanoSystems Institute.
Contact Information:
Robert Damoiseaux, Director
Phone: (310) 794-1974
Email: rdamoiseaux@mednet.ucla.edu
Scientific Advisors
Owen Witte, MD
Jing Huang, PhD
The MSSR is located at 2145 California (N)anoSystems Institute (CNSI).
- High-Throughput-Screening
- Drug Discovery
- Functional Genomics & Novel Applications
- User base includes: Small BioTech, Big Pharma, Academics, NIH
- Chemical Libraries: 180,000 compounds of drug-like molecules with emphasis on desirable target classes such as kinases, proteases, phosphatases, GPCRs and ion channel
- cDNA overexpression library of 16,000 clones accessible as "expression-ready" sets
- Plater reader based readouts and high content screening
Work performed at the MSSR has supported numerous publications in top notch journals such as Nature Biotechnology, Science, PNAS, amongst others